WP2: Fabrication and Characterization of Si NW FETs Array

 
The overreaching goal of this WP is to develop arrays of chemically-sensitive field effect transistors (FETs) of molecule-terminated silicon nanowires (Si NWs) and to test the feasibility of the developed devices for sensing volatile biomarkers of LC from in-vitro tissues and from human exhaled breath. More specifically, the objectives of WP2 will be:

  • Having a set of fully functionalized Si NWs.
  • Achieving a set of highly-efficient fabrication processes for Si NW FET devices.
  • Determining the most informative device parameters.
  • Determining the relationship between (i) the electrical and/or sensing parameters and (ii) sensor specifics.
  • Having a set of pattern recognition models which have been successfully used to analyze the output signals of the sensor array.
  • Understanding of the signal transduction mechanism of the various volatile biomarkers and metabolites.
  • Testing SiNW FETs array, with proven ability to sense volatile biomarkers of pre- and post-cancerous conditions, from in-vitro tissues and from exhaled human breath.
  • Testing the performance of the Si NW FETs after integration in a microfludic cell.
  • Testing the performance of the Si NW FETs after integration in a stand-alone ‘NA-NOSE’.